Per- and Polyfluoroalkyl Substances (PFAS) and Their Toxicology as Evidenced Through Disease and Biomarkers

Per- and polyfluoroalkyl substances (PFAS) are a group of at least 4730 chemicals with clearly important surfactant properties. They used in coatings, paints, stain repellents, firefighting foams as well other industrial processes. Their high use recalcitrance to degradation coupled their lipophilicity bioaccumulation makes them persistent organic pollutants or forever chemicals. In turn, they measured the serum most humans, especially long-chain PFAS. The toxicity PFASs have not been studied, USEPA is starting National PFAS-testing strategy prioritize PFAS testing because all feasible. Some such PFOA PFOS currently banned many countries persistence bioaccumulation. Many observed environment bioconcentrate aquatic food webs. These associated immunotoxicity, cardiovascular disease, liver reproductive developmental disorders, human health issues.